Elevated Plasma Level of Soluble F11 Receptor/Junctional Adhesion Molecule-A (F11R/JAM-A) in Hypertension
نویسندگان
چکیده
منابع مشابه
Elevated plasma level of soluble F11 receptor/junctional adhesion molecule-A (F11R/JAM-A) in hypertension.
BACKGROUND The F11 receptor (F11R, also known as junctional adhesion molecule A (JAM-A)) plays a role in the development of hypertension in rat. Genetic variants in the human F11R gene were demonstrated to influence systolic blood pressure. In the present study, we investigated the relationship between F11R and hypertension by examining the levels of a circulating soluble form of F11R (sF11R) i...
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OBJECTIVES The purpose of this study was to determine the association of the F11 receptor (F11R) with human vascular disease. BACKGROUND A molecule identified as critical for platelet adhesion to a cytokine-inflamed endothelial surface in vitro is F11R. The F11R is known to be expressed in platelets and endothelium and reported recently to be overexpressed in atherosclerotic plaques. METHOD...
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ژورنال
عنوان ژورنال: American Journal of Hypertension
سال: 2009
ISSN: 0895-7061,1941-7225
DOI: 10.1038/ajh.2009.23